Amphotericin B deoxycholate
Neonatal Route/Dilution

Neonatal Route/Dilution

Route

IV

Final Dilution

Peripheral Lines

0.1 mg/mL

Central Lines

0.2 mg/mL

Dilution Instructions

Reconstitute 50 mg vial with 10 mL of Sterile water for injection = 5 mg/mL, then

  • Mix 29.4 mL of D5W or D10W with 0.6 mL of
    5 mg/mL concentration in a 30 mL empty sterile vial = 0.1 mg/mL
  • Mix 28.8 mL of D5W or D10W with 1.2 mL of
    5 mg/ml concentration in a 30 mL empty sterile vial = 0.2 mg/mL

Stability

5 mg/mL = 12H refrigerate
0.1 mg/mL = 24H room temperature
0.2 mg/mL = 24H room temperature