Cefuroxime

C difficile risk
Medium
Oral Bioavailability
Moderate

Dosing

750 - 1500 mg IV q8h

500 mg PO BID

0 - 30 eGFR30+ eGFRNo dose adjustment required500 mg PO BID

0 - 25 eGFR25 - 50 eGFR50+ eGFR750 - 1500 mg IV q12 - 24h750 - 1500mg IV q8 - 12h750 - 1500 mg IV q8h

General Information

  • Community acquired pneumonia

  • Pharyngitis/tonsillitis

  • Sinusitis

  • COPD exacerbations

Pregnancy: Compatible.

Breastfeeding: Compatible.

  • Allergy (immediate & delayed)

  • Positive Coombs

  • Cytopenias

  • GI upset

  • Diarrhea

  • Abnormal liver enzymes

None significant

Tablet should be given with food to increase absorption.

Antimicrobial class: 2nd Generation Cephalosporin