Antimicrobials
Cephalexin

Cephalexin

Medium
Excellent

General Information

Pregnancy: Compatible.

Breastfeeding: Compatible.

  • Skin and soft tissue infection
  • MSSA infections
  • Urinary tract infections
  • Allergy/rash (immediate or delayed).
  • Gastrointestinal intolerance.
  • Can cause positive Coombs, cytopenias, eosinophilia, and hepatic and renal laboratory abnormalities.

Amoxicillin and ampicillin share a common structural side chain with cephalexin, therefore, there is an increased risk of cross allergy between these agents.

  • Please see penicillin and beta lactam allergy management and cross reactivity tool.

Increases metformin levels.

Antimicrobial class: First generation cephalosporin - oral