IV: 600 - 900 mg IV q8h
PO: 300 - 450 mg PO TID - QID
300 mg PO BID x 7 days
MUST confirm GBS is sensitive to clindamycin before use900 mg IV q8h until delivery
900 mg IV once 30 min prior to skin incision (re-dose if blood loss > 1500 mL during procedure)
900 mg IV q8h (in combination with an appropriate beta lactam)
Infuse over 15 minutes
Age 0-4 wk5 mg/kg/dose IV Q12H
Age 0-7 days>7 days5 mg/kg/dose IV Q12H5 mg/kg/dose IV Q8H
Age 0-7 days>7 days5 mg/kg/dose IV Q8H5 mg/kg/dose IV Q6H
All Infants: 5 mg/kg/dose IV Q6H
IV, IM, PO
6 mg/mL
Mix 6mL of D5W with 0.25mL of 150 mg/mL concentration in a 10mL empty sterile vial = 6 mg/mL
150 mg/mL = 24H
6 mg/mL = 24H
Refrigerate
Gram positive skin and soft tissue infections including necrotizing fasciitis as an adjunctive agent to a beta lactam for reducing toxin production.
Skin & soft tissue infections involving susceptible MRSA.
Susceptible infections and surgical prophylaxis in setting of IgE mediated beta-lactam allergy.
For decreasing toxin production in toxic shock syndrome.
Clindamycin may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents.
