Guidelines
Treatment

Treatment

Standard Regimen

  • 5 million units IV once STAT, THEN
  • 2.5 million units IV every 4 hours until delivery

Penicillin Allergy

  • 2g IV once STAT, THEN
  • 1g IV every 8 hours until delivery

Alternatives

If documented cefazolin allergy or type IV hypersensitivity reaction (e.g. Stevens-Johnson Syndrome) to beta lactams

  • 900mg IV STAT, THEN
  • 900mg IV every 8 hours until delivery

OR

  • 1g IV STAT, THEN
  • 1g IV every 12 hours until delivery