Steroids during ALL induction/re-induction may prevent fever with infection. If ill and neutropenic, treat according to the algorithm even in absence of fever.
This algorithm applies to patients with unclear source of fever. If suspected source or organism isolated, direct therapy toward organisms/source.
Fever ≥38°C AND ANC <500 cells/mL Note - Do not delay antibiotics for ANC confirmation
Renal adjustment in pediatric section in monograph
CONSIDER
48 Hour Follow-up: Bacterial Organism Identified Target antimicrobials to organism and susceptibilities when available 48 Hour Follow-up: Bacterial Organism Not Identified Continue cefepime ONLY